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FEATURES

FAMILY

aspartate-semialdehyde dehydrogenase family

DESCRIPTION

Also known as MCR_SULTO, mcr, scr. Catalyzes the reduction of malonyl-CoA to malonate semialdehyde, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutyrate cycles. Can also use succinyl-CoA and succinate semialdehyde as substrates but at a lower rate than malonyl-CoA. Homodimer and possibly a tetramer.

Also known as MCR_SULTO, mcr, scr. Catalyzes the reduction of malonyl-CoA to malonate semialdehyde, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutyrate cycles. Can a ...

EXTERNAL LINKS

uniprot
enzyme classification

mcr

Malonyl-CoA reductase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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