FEATURES

FAMILY

DESCRIPTION

Also known as DDP1_YEAST, DDP1. May eliminate potentially toxic dinucleoside polyphosphates during sporulation. Most active against diadenosine 5', 5'''-P1, P6-hexaphosphate (Ap6A). Can also hydrolyze diadenosine 5', 5'''-P1, P5-pentaphosphate (Ap5A), adenosine 5'-pentaphosphate, and adenosine 5'-tetraphosphate are also substrates, but not diadenosine 5', 5'''-P1, P4-tetraphosphate (Ap4A) or other dinucleotides, mononucleotides, nucleotide sugars, or nucleotide alcohols. Also cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate).

EXTERNAL LINKS

DDP1

Diphosphoinositol polyphosphate phosphohydrolase DDP1

Mutations

Mutation(s) distribution

Mutations table

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