FEATURES

DESCRIPTION

Also known as HRP1_YEAST, HRP1, NAB4, NAB5. RNA-binding protein, which is involved in the polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor CFIA complex and the cleavage and polyadenylation factor (CPF) complex. May be involved in regulation of poly(A) site selection. Is involved in nonsense-mediated mRNA decay. Seems to bind to an RNA downstream sequence element (DSE) located 3' of a nonsense codon and may mark the transcript for decay. Interacts with NAM7.

EXTERNAL LINKS

uniprot
enzyme classification

HRP1

Nuclear polyadenylated RNA-binding protein 4

Mutations

Mutation(s) distribution

Mutations table

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