FEATURES

FAMILY

DESCRIPTION

Also known as PFD5_HUMAN, PFDN5, MM1, PFD5. Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. Binds to MYC; interacts with its N-terminal domain.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PFDN5

Prefoldin subunit 5

PFDN5

Molecular Synopsis