FEATURES

FAMILY

DESCRIPTION

Also known as RNZ2_HUMAN, ELAC2, HPC2. Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (PubMed:21593607). Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly (PubMed:24703694). Homodimer (By similarity). Interacts with PTCD1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ELAC2

Zinc phosphodiesterase ELAC protein 2

ELAC2

Molecular Synopsis