FEATURES

FAMILY

DESCRIPTION

Also known as TXD17_HUMAN, TXNDC17, TXNL5. Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. Interacts with TRXR1 and DYNLL1/DNCL1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TXNDC17

Thioredoxin domain-containing protein 17

TXNDC17

Molecular Synopsis