FEATURES

FAMILY

DESCRIPTION

Also known as PXL2A_HUMAN, PRXL2A, C10orf58, FAM213A, PAMM. Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880).

Also known as PXL2A_HUMAN, PRXL2A, C10orf58, FAM213A, PAMM. Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880) ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PRXL2A

Peroxiredoxin-like 2A

PRXL2A

Molecular Synopsis