FEATURES

FAMILY

DESCRIPTION

Also known as RAMAC_HUMAN, RAMAC, C15orf18, FAM103A1, RAMMET. Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs (PubMed:22099306, PubMed:27422871). Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT (PubMed:27422871). Regulates RNMT expression by a post-transcriptional stabilizing mechanism (PubMed:22099306). Binds RNA (PubMed:22099306). Interacts with RNMT; this interaction enhances mRNA binding and cap methyltransferase activity.

Also known as RAMAC_HUMAN, RAMAC, C15orf18, FAM103A1, RAMMET. Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RAMAC

RNA guanine-N7 methyltransferase activating subunit

RAMAC

Molecular Synopsis