FEATURES

DESCRIPTION

Also known as FAP24_HUMAN, FAAP24, C19orf40. Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA. Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9, FANCM and FAAP24. Interacts with FANCM.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FAAP24

Fanconi anemia core complex-associated protein 24

FAAP24

Molecular Synopsis