FEATURES

FAMILY

DESCRIPTION

Also known as CPLN2_HUMAN, CPLANE2, C1orf89, RSG1. Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CPLANE2

Ciliogenesis and planar polarity effector 2

CPLANE2

Molecular Synopsis