FEATURES

FAMILY

DESCRIPTION

Also known as SFXN3_HUMAN, SFXN3. Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SFXN3

Sideroflexin-3

SFXN3

Molecular Synopsis