FEATURES

FAMILY

DESCRIPTION

Also known as LFG2_HUMAN, FAIM2, KIAA0950, LFG, LFG2, NMP35, TMBIM2. Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. Interacts with FAS/TNFRSF6 and BAX.

Also known as LFG2_HUMAN, FAIM2, KIAA0950, LFG, LFG2, NMP35, TMBIM2. Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons b ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FAIM2

Protein lifeguard 2

FAIM2

Molecular Synopsis