FEATURES

FAMILY

DESCRIPTION

Also known as HINT2_HUMAN, HINT2. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:16762638, PubMed:31990367). Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA) (PubMed:16762638). Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro (PubMed:31990367). May be involved in steroid biosynthesis (PubMed:18653718). May play a role in apoptosis (PubMed:16762638).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HINT2

Adenosine 5'-monophosphoramidase HINT2

HINT2

Molecular Synopsis