FEATURES

FAMILY

DESCRIPTION

Also known as SRXN1_HUMAN, SRXN1, C20orf139, SRX, SRX1. Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SRXN1

Sulfiredoxin-1

SRXN1

Molecular Synopsis