FEATURES

FAMILY

DESCRIPTION

Also known as PANK2_HUMAN, PANK2, C20orf48. Catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis (PubMed:15659606, PubMed:17825826, PubMed:17242360, PubMed:16272150). Required for angiogenic activity of umbilical vein of endothelial cells (HUVEC) (PubMed:30221726)., Catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PANK2

Pantothenate kinase 2, mitochondrial

PANK2

Molecular Synopsis