FEATURES

FAMILY

DESCRIPTION

Also known as RABL3_MOUSE, Rabl3. Required for KRAS signaling regulation and modulation of cell proliferation (PubMed:31406347). Regulator of KRAS prenylation, and probably prenylation of other small GTPases (By similarity). Required for lymphocyte development and function (PubMed:32220963). Not required for myeloid cell development (PubMed:32220963). Homodimer (PubMed:32220963). Interacts with GPR89; the interaction stabilizes GPR89 (PubMed:32220963). Interacts with RAP1GDS1 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

Rabl3

Mutations

Mutation(s) distribution

Mutations table