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FEATURES

FAMILY

HMG-CoA synthase family

DESCRIPTION

Also known as HMGCS_ENTFL, mvaS. Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds. Homodimer.

Also known as HMGCS_ENTFL, mvaS. Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA). Functions in the mevalonate (MVA) pathway leading to i ...

EXTERNAL LINKS

uniprot
enzyme classification

mvaS

Hydroxymethylglutaryl-CoA synthase

Molecular Synopsis

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