FEATURES

FAMILY

DESCRIPTION

Also known as SP130_HUMAN, SAP130. Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. Component of a mSin3A corepressor complex that contains SIN3A, SAP130, SUDS3/SAP45, ARID4B/SAP180, HDAC1 and HDAC2. Interacts (released by dead or dying cells) with CLEC4E (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SAP130

Histone deacetylase complex subunit SAP130

SAP130

Molecular Synopsis