FEATURES

FAMILY

DESCRIPTION

Also known as SRMS_HUMAN, SRMS, C20orf148. Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues (PubMed:23822091). Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues (PubMed:29496907). Phosphorylation of KHDRBS1 is EGF-dependent (PubMed:29496907). Interacts (via the SH2 and SH3 domains) with DOK1 (PubMed:23822091). Interacts with KHDRBS1/SAM68 and VIM (PubMed:29496907).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SRMS

Tyrosine-protein kinase Srms

SRMS

Molecular Synopsis