FEATURES

FAMILY

DESCRIPTION

Also known as OSGP2_HUMAN, OSGEPL1, GCP1. Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

OSGEPL1

Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

OSGEPL1

Molecular Synopsis