FEATURES

DESCRIPTION

Also known as CDCP1_HUMAN, CDCP1, TRASK. May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis. Interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. Also interacts with SRC and PRKCG/protein kinase C gamma.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CDCP1

CUB domain-containing protein 1

CDCP1

Molecular Synopsis