FEATURES

FAMILY

DESCRIPTION

Also known as SYNCI_HUMAN, SYNC, SYNC1. Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF proteins. May link the dystrophin-associated glycoprotein complex (DAPC) to intracellular desmin (DES) filaments. Interacts with DES and DTNA.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SYNC

Syncoilin

SYNC

Molecular Synopsis