FEATURES

FAMILY

DESCRIPTION

Also known as A4GAT_RAT, A4galt. Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)) (PubMed:10854428). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer (By similarity). Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

A4galt

Lactosylceramide 4-alpha-galactosyltransferase

A4galt

Molecular Synopsis