FEATURES

FAMILY

DESCRIPTION

Also known as MED20_CAEEL, mdt-20. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Component of the Mediator complex.

EXTERNAL LINKS

uniprot
enzyme classification

mdt-20

Mediator of RNA polymerase II transcription subunit 20

mdt-20

Molecular Synopsis