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FAMILY

5'(3')-deoxyribonucleotidase family

DESCRIPTION

Also known as NT5M_HUMAN, NT5M, DNT2. Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. Homodimer.

Also known as NT5M_HUMAN, NT5M, DNT2. Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from exces ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NT5M

5'(3')-deoxyribonucleotidase, mitochondrial

Mutations

Mutation(s) distribution

Mutations table

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