FEATURES

FAMILY

DESCRIPTION

Also known as CHSTB_HUMAN, CHST11. Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CHST11

Carbohydrate sulfotransferase 11

CHST11

Molecular Synopsis