FEATURES

FAMILY

DESCRIPTION

Also known as HINT3_HUMAN, HINT3. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:17870088). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase (PubMed:17870088). Hydrolyzes 3-indolepropionic acyl-adenylate and fluorogenic purine nucleoside tryptamine phosphoramidates in vitro (PubMed:17870088). Forms dimers to octamers and even larger oligomer (PubMed:17870088). Interacts with CALM1 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HINT3

Adenosine 5'-monophosphoramidase HINT3

HINT3

Molecular Synopsis