FEATURES

DESCRIPTION

Also known as ANLN_HUMAN, ANLN. Required for cytokinesis (PubMed:16040610). Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase and anaphase of mitosis (PubMed:23870127). May play a significant role in podocyte cell migration (PubMed:24676636). Interacts with F-actin (PubMed:10931866). Interacts with CD2AP (PubMed:15800069). May interact with RHOA (PubMed:16357138). Interacts with FZR1/CDH1 during mitotic exit (PubMed:16040610).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ANLN

Anillin

ANLN

Molecular Synopsis