FEATURES

DESCRIPTION

Also known as DUOX1_HUMAN, DUOX1, DUOX, LNOX1, THOX1. Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain. Interacts with TXNDC11, TPO and CYBA.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DUOX1

Dual oxidase 1

DUOX1

Molecular Synopsis