FEATURES

FAMILY

DESCRIPTION

Also known as OLFL3_HUMAN, OLFML3. Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

OLFML3

Olfactomedin-like protein 3

OLFML3

Molecular Synopsis