FEATURES

FAMILY

1-acyl-sn-glycerol-3-phosphate acyltransferase family

DESCRIPTION

Also known as PLCD_HUMAN, AGPAT4. Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1, 2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

AGPAT4

1-acyl-sn-glycerol-3-phosphate acyltransferase delta

AGPAT4

Molecular Synopsis