FEATURES

FAMILY

DESCRIPTION

Also known as SMC4_HUMAN, SMC4, CAPC, SMC4L1. Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Forms a heterodimer with SMC2. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG.

EXTERNAL LINKS

SMC4

Structural maintenance of chromosomes protein 4

Structural Ligandability

Domains Chains

0 chains assessed

1 chain not associated with a domain

SMC4

Structural Ligandability

Domains Chains

Distribution