FEATURES

FAMILY

DESCRIPTION

Also known as TM39A_HUMAN, TMEM39A, SUSR2. Regulates autophagy by controlling the spatial distribution and levels of the intracellular phosphatidylinositol 4-phosphate (PtdIns(4)P) pools (PubMed:31806350). Modulates (PtdIns(4)P) levels by regulating the ER-to-Golgi trafficking of the phosphatidylinositide phosphatase SACM1L (PubMed:31806350)., (Microbial infection) Positively regulates the replication of encephalomyocarditis virus (EMCV) via autophagy-dependent pathway. Interacts with SACM1L, SEC23A and SEC24A.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TMEM39A

Transmembrane protein 39A

TMEM39A

Molecular Synopsis