FEATURES

FAMILY

DESCRIPTION

Also known as BCLF1_HUMAN, BCLAF1, BTF, KIAA0164. Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA. Component of the SNARP complex which consists at least of SNIP1, SNW1, THRAP3, BCLAF1 and PNN. Component of a MACOM-like complex, named WTAP complex, composed of WTAP, ZC3H13, CBLL1, KIAA1429, RBM15, BCLAF1 and THRAP3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

BCLAF1

Bcl-2-associated transcription factor 1

BCLAF1

Molecular Synopsis