FEATURES

FAMILY

DESCRIPTION

Also known as AHSP_HUMAN, AHSP, EDRF, ERAF. Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia. Monomer. Forms a heterodimer with free alpha-hemoglobin. Does not bind beta-hemoglobin nor alpha(2)beta(2) hemoglobin A.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

AHSP

Alpha-hemoglobin-stabilizing protein

AHSP

Molecular Synopsis