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FEATURES

FAMILY

GEF (guanine exchange factor) SopE family

DESCRIPTION

Also known as SOPE_SALTI, sopE. Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells (By similarity).

Also known as SOPE_SALTI, sopE. Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in acti ...

EXTERNAL LINKS

uniprot
enzyme classification

sopE

Guanine nucleotide exchange factor SopE

Structural Ligandability

Domains Chains

Distribution

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