FEATURES

FAMILY

class I fructose-bisphosphate aldolase family

DESCRIPTION

Also known as ALFC6_ARATH, FBA6. Fructose-bisphosphate aldolase that plays a key role in glycolysis and gluconeogenesis (PubMed:21782461). Associates with GAPC1 to the outer mitochondrial membrane, in a redox-dependent manner, leading to binding and bundling of actin. Actin binding and bundling occurs under oxidizing conditions and is reversible under reducing conditions. May be part of a redox-dependent retrograde signal transduction network for adaptation upon oxidative stress (PubMed:23316205). Homotetramer (By similarity). Interacts with TRX1 and TRX3 (PubMed:21782461). Interacts with GAPC1 AND VDAC3 (PubMed:23316205).

EXTERNAL LINKS

FBA6

Mutations

Mutation(s) distribution

Mutations table