FEATURES

FAMILY

DESCRIPTION

Also known as ZRK1_ARATH, ZRK1, QRX3, RKS1. Serine/threonine-protein kinase that confers a broad-spectrum quantitative disease resistance (QDR) to the pathogenic biotrophic bacteria Xanthomonas campestris (e.g. pv. campestris (Xcc), pv. raphani, pv. armoriaceae and pv. incanae) by restricting bacterial spread to the vascular system from the infection site; X.campestris causes black rot disease in crops (PubMed:24068949, PubMed:26355215, PubMed:30948526). Seems to not have any kinase activity (PubMed:24068949). Component of a stable high-order oligomeric complex made of RKS1 and RPP13L4/ZAR1 which recruits Xanthomonas campestris effector XopAC/AvrAC-mediated uridylylated PBL2 in the presence of ATP to form a wheel-like pentameric resistosome; this complex triggers immunity toward X.campestris in vascular tissues (PubMed:26355215, PubMed:30948527, PubMed:30948526). Interacts with RPP13L4/ZAR1 and uridylylated PBL2 (PubMed:26355215, PubMed:30948526).

EXTERNAL LINKS

ZRK1

Mutations

Mutation(s) distribution

Mutations table