FEATURES

FAMILY

DESCRIPTION

Also known as DYH17_HUMAN, DNAH17, DNAHL1, DNEL2. Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (Probable). Plays a major role in sperm motility, implicated in sperm flagellar assembly and beating (PubMed:31178125). Consists of at least two heavy chains and a number of intermediate and light chains.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DNAH17

Dynein axonemal heavy chain 17

DNAH17

Molecular Synopsis