FEATURES

FAMILY

DESCRIPTION

Also known as SCOC_HUMAN, SCOC, SCOCO. Positive regulator of amino acid starvation-induced autophagy. Homodimer (PubMed:24098481). Interacts with ARL1, ARL2 and ARL3 (PubMed:11303027). Directly interacts with FEZ1 and UVRAG (PubMed:22354037, PubMed:24098481). The interaction with UVRAG is reduced by amino acid starvation, but the complex is stabilized in the presence of FEZ1. Interacts with NRBF2 (PubMed:22354037).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SCOC

Short coiled-coil protein

SCOC

Molecular Synopsis