FEATURES

FAMILY

DESCRIPTION

Also known as LCAP_HUMAN, LNPEP, OTASE. Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain. Homodimer. Binds tankyrases 1 and 2.

Also known as LCAP_HUMAN, LNPEP, OTASE. Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

LNPEP

Mutations

Mutation(s) distribution

Mutations table