FEATURES

FAMILY

DESCRIPTION

Also known as KI26A_HUMAN, KIF26A, KIAA1236. Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity). Interacts with GRB2 (via SH2 domain).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KIF26A

Kinesin-like protein KIF26A

KIF26A

Molecular Synopsis