FEATURES

FAMILY

DESCRIPTION

Also known as NDRG4_HUMAN, NDRG4, BDM1, KIAA1180. Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NDRG4

Protein NDRG4

NDRG4

Molecular Synopsis