FEATURES

FAMILY

DESCRIPTION

Also known as RAB26_HUMAN, RAB26. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland. Interacts with RIMS1 (By similarity). Interacts with ADRA2B.

EXTERNAL LINKS

RAB26

Ras-related protein Rab-26

RAB26

Molecular Synopsis