FEATURES

FAMILY

rRNA adenine N(6)-methyltransferase family

DESCRIPTION

Also known as DIM1_HUMAN, DIMT1, DIMT1L. Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle (PubMed:25851604). Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DIMT1

Probable dimethyladenosine transferase

Mutations

Mutation(s) distribution

Mutations table

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