FEATURES

FAMILY

DESCRIPTION

Also known as EXOC7_HUMAN, EXOC7, EXO70, KIAA1067. Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity). It is required for neuron survival and plays an essential role in cortical development (By similarity). The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with ARHQ in a GTP-dependent manner. Interacts with RAB11FIP3 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EXOC7

Exocyst complex component 7

EXOC7

Molecular Synopsis