FEATURES

FAMILY

DESCRIPTION

Also known as CNTN6_HUMAN, CNTN6. Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity). Interacts with PTPRG.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CNTN6

Contactin-6

CNTN6

Molecular Synopsis