FEATURES

FAMILY

U2 small nuclear ribonucleoprotein A family

DESCRIPTION

Also known as RU2A_DROME, U2A. Involved in pre-mRNA splicing as component of the spliceosome (By similarity). Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (By similarity). In the germ line, has a role in oogenesis, by regulating spermatogenesis and nurse cell nuclei chromatin decondensation and dispersal, probably by regulating the splicing of proteins necessary for germline differentiation such as the meiotic protein mei-P26 (PubMed:27035939, PubMed:24244416). Interacts with the SMN complex.

EXTERNAL LINKS

uniprot
enzyme classification

U2A

Mutations

Mutation(s) distribution

Mutations table