FEATURES

FAMILY

DESCRIPTION

Also known as TSAB_THEMA, tsaB. Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Homodimer (PubMed:20944216). Forms an hexamer composed of two TsaB, TsaD and TsaE trimers (PubMed:29741707).

EXTERNAL LINKS

tsaB

tRNA threonylcarbamoyladenosine biosynthesis protein TsaB

Mutations

Mutation(s) distribution

Mutations table

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