FEATURES

FAMILY

cation transport ATPase (P-type) (TC 3.A.3) family

DESCRIPTION

Also known as AT11B_HUMAN, ATP11B, ATPIF, ATPIR, KIAA0956. Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes (PubMed:30018401). May contribute to the maintenance of membrane lipid asymmetry in endosome compartment (PubMed:30018401). Component of a P4-ATPase flippase complex which consists of a catalytic alpha subunit ATP11B and an accessory beta subunit TMEM30A.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ATP11B

Phospholipid-transporting ATPase IF

ATP11B

Molecular Synopsis